Improved health and survival of FIV-infected cats is associated with the presence of autoantibodies to the primary receptor, CD134.

@article{Grant2009ImprovedHA,
  title={Improved health and survival of FIV-infected cats is associated with the presence of autoantibodies to the primary receptor, CD134.},
  author={Chris K. Grant and Elizabeth A Fink and Magnus Sundstrom and Bruce E. Torbett and John H. Elder},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 47},
  pages={19980-5}
}
We analyzed antibody responses in sera from feline immunodeficiency virus (FIV)-infected and uninfected cats. A strong antiviral response to the viral surface glycoprotein (SU) was noted in both natural and experimental infections. In addition, 143 of 226 FIV-infected animals (63%) also expressed antibodies to the primary binding receptor, CD134, whereas cats infected with other feline RNA viruses, including calicivirus, coronavirus, herpesvirus, and feline leukemia virus, did not. Both… CONTINUE READING