Improved glucosamine and N-acetylglucosamine production by an engineered Escherichia coli via step-wise regulation of dissolved oxygen level.

@article{Chen2012ImprovedGA,
  title={Improved glucosamine and N-acetylglucosamine production by an engineered Escherichia coli via step-wise regulation of dissolved oxygen level.},
  author={Xin Chen and Long Liu and Jianghua Li and Guocheng Du and Jian Chen},
  journal={Bioresource technology},
  year={2012},
  volume={110},
  pages={534-8}
}
Influence of dissolved oxygen (DO) levels (10%, 20%, 30% and 40%) on the glucosamine (GlcN) and N-acetylglucosamine (GlcNAc) production by recombinant Escherichia coli was investigated. It was found that the highest specific GlcN and GlcNAc production rates were obtained at different DO levels at different culture stages. Namely, the highest specific GlcN and GlcNAc production rates were obtained at 20% during 0-2h, 30% during 2-8h, 40% during 8-12h, and 30% during 12-18h. Accordingly, a step… CONTINUE READING

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