Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector

Abstract

The establishment of efficient gene delivery to target human tissue is a major obstacle for transition of gene therapy from the pre-clinical phases to the clinic. The poor long-term patency rates for coronary artery bypass grafting (CABG) is a major clinical problem that lacks an effective and proven pharmacological intervention. Late vein graft failure… (More)

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@article{Work2004ImprovedGD, title={Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector}, author={Lorraine M. Work and Paul N. Reynolds and Andrew H. Baker}, journal={Genetic Vaccines and Therapy}, year={2004}, volume={2}, pages={14 - 14} }