Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering.

@article{Lee2011ImprovedGF,
  title={Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering.},
  author={K Lee and Min-Eui Hong and Suk-Chae Jung and Suk-Jin Ha and Byung Jo Yu and Hyun Min Koo and Sung Min Park and Jin-Ho Seo and D K Kweon and Jae Chan Park and Yong-Su Jin},
  journal={Biotechnology and bioengineering},
  year={2011},
  volume={108 3},
  pages={621-31}
}
Although Saccharomyces cerevisiae is capable of fermenting galactose into ethanol, ethanol yield and productivity from galactose are significantly lower than those from glucose. An inverse metabolic engineering approach was undertaken to improve ethanol yield and productivity from galactose in S. cerevisiae. A genome-wide perturbation library was introduced into S. cerevisiae, and then fast galactose-fermenting transformants were screened using three different enrichment methods. The… CONTINUE READING
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