Improved functional recovery with oxandrolone after spinal cord injury in rats.

@article{Zeman2009ImprovedFR,
  title={Improved functional recovery with oxandrolone after spinal cord injury in rats.},
  author={Richard J. Zeman and William A. Bauman and Xialing Wen and Nengtai Ouyang and Joseph D. Etlinger and C P Cardozo},
  journal={Neuroreport},
  year={2009},
  volume={20 9},
  pages={864-8}
}
At present, only the corticosteroid, methylprednisolone, is used for acute spinal cord injury to improve function. However, improvements are modest, and are associated with myopathy and immunosuppression so that alternative treatments are needed. Oxandrolone is an androgenic steroid with potential neuroprotective properties that is used to prevent muscle loss and is not immunosuppressive. Oxandrolone increased locomotor recovery concomitant with reduced loss of cord tissue in a standard weight… CONTINUE READING