Improved endothelialization and reduced thrombosis by coating a synthetic vascular graft with fibronectin and stem cell homing factor SDF-1α.

Abstract

Failure of synthetic small-diameter vascular grafts is determined mainly by the lack of endothelial cells, as these cells inhibit thrombosis and intimal hyperplasia. Coating of graft material with homing factors for circulating stem cells has the potential to improve endogenous endothelialization of these grafts and to reduce graft failure. Synthetic… (More)
DOI: 10.1016/j.actbio.2011.09.016

Topics

Cite this paper

@article{Visscher2012ImprovedEA, title={Improved endothelialization and reduced thrombosis by coating a synthetic vascular graft with fibronectin and stem cell homing factor SDF-1α.}, author={Geofrey De Visscher and Lindsay Mesure and Bart Meuris and Asya Ivanova and Willem J. Flameng}, journal={Acta biomaterialia}, year={2012}, volume={8 3}, pages={1330-8} }