Improved endothelial function and decreased levels of endothelium-derived microparticles after transcatheter aortic valve implantation.

@article{Horn2015ImprovedEF,
  title={Improved endothelial function and decreased levels of endothelium-derived microparticles after transcatheter aortic valve implantation.},
  author={Patrick Horn and Daniel Stern and Verena Veulemans and Christian Heiss and Tobias Zeus and Marc W. Merx and Malte Kelm and Ralf Westenfeld},
  journal={EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology},
  year={2015},
  volume={10 12},
  pages={1456-63}
}
AIMS Degenerative aortic valve stenosis (AVS) is independently associated with endothelial dysfunction and increased levels of circulating endothelium-derived microparticles (EMPs) as a marker of compromised endothelial integrity. The aim of this study was to investigate whether therapy for severe AVS by transcatheter aortic valve implantation (TAVI) improves endothelial function and decreases EMPs. METHODS AND RESULTS Fifty-six patients with indication for TAVI due to symptomatic severe AVS… CONTINUE READING
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