Improved embryo development with decreased apoptosis in blastomeres after the treatment of cloned bovine embryos with beta-mercaptoethanol and hemoglobin.

@article{Park2004ImprovedED,
  title={Improved embryo development with decreased apoptosis in blastomeres after the treatment of cloned bovine embryos with beta-mercaptoethanol and hemoglobin.},
  author={Eul Soon Park and Woo Suk Hwang and Sung keun Kang and Byeong Chun Lee and Jae Yong Han and Jeong Mook Lim},
  journal={Molecular reproduction and development},
  year={2004},
  volume={67 2},
  pages={200-6}
}
In preliminary experiments, the treatment of donor somatic cells with beta-mercaptoethanol (ME) or hemoglobin (Hb) improved in vitro-development of bovine cloned embryos. This study was subsequently evaluated whether the exposure to Hb and/or ME during in vitro-maturation or embryo culture could further promote the development of embryos cloned with ME-treated donor cells. A prospective, randomized study was conducted and, embryo development, cell number, and apoptosis in blastocysts were… CONTINUE READING