Improved dendritic cell-based immunization against hepatitis C virus using peptide inhibitors of interleukin 10.

Abstract

UNLABELLED The high levels of interleukin 10 (IL-10) present in chronic hepatitis C virus (HCV) infection have been suggested as responsible for the poor antiviral cellular immune responses found in these patients. To overcome the immunosuppressive effect of IL-10 on antigen-presenting cells such as dendritic cells (DCs), we developed peptide inhibitors of… (More)
DOI: 10.1002/hep.23980

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Cite this paper

@article{DazValds2011ImprovedDC, title={Improved dendritic cell-based immunization against hepatitis C virus using peptide inhibitors of interleukin 10.}, author={Nancy D{\'i}az-Vald{\'e}s and Lorea Manterola and Virginia Bels{\'u}e and Jos{\'e} Ignacio Riezu-Boj and Esther Larrea and Itziar Echeverria and Diana Ll{\'o}piz and Jacinto L{\'o}pez-Sagaseta and Herv{\'e} Lerat and Jean-Michel Pawlotsky and Jes{\'u}s Prieto and Juan J Lasarte and Francisco Borr{\'a}s-Cuesta and Pablo Sarobe}, journal={Hepatology}, year={2011}, volume={53 1}, pages={23-31} }