Improved contractility of obstructed bladders after Tadenan treatment is associated with reversal of altered myosin isoform expression.

@article{Gomes2000ImprovedCO,
  title={Improved contractility of obstructed bladders after Tadenan treatment is associated with reversal of altered myosin isoform expression.},
  author={Cristiano Mendes Gomes and Michael E Disanto and Pat Horan and Robert M Levin and Alan J. Wein and Samuel Chacko},
  journal={The Journal of urology},
  year={2000},
  volume={163 6},
  pages={
          2008-13
        }
}
PURPOSE Tadenan is a plant extract from Pygeum africanum used in the treatment of benign prostatic hyperplasia, to protect the bladder from contractile dysfunction induced by partial bladder outlet obstruction (BOO). The aim of the present study was to determine whether the Tadenan-induced return of detrusor contractility affects the expression of myosin isoforms, which differ at the C-terminal (SM1 and SM2) and the N-terminal regions (SM-A and SM-B). MATERIALS AND METHODS Four groups of New… CONTINUE READING
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