Improved bone healing by angiogenic factor-enriched platelet-rich plasma and its synergistic enhancement by bone morphogenetic protein-2.

@article{Park2008ImprovedBH,
  title={Improved bone healing by angiogenic factor-enriched platelet-rich plasma and its synergistic enhancement by bone morphogenetic protein-2.},
  author={Eun-Jin Park and Eun-seok Kim and Hans-Peter Weber and Robert F. Wright and David J Mooney},
  journal={The International journal of oral & maxillofacial implants},
  year={2008},
  volume={23 5},
  pages={818-26}
}
PURPOSE The purpose of this study was to modify the method of platelet-rich plasma (PRP) preparation for obtaining optimal angiogenic potential and accelerate bone healing. Also, the potential synergistic effect of a suboptimal concentration of bone morphogenic protein-2 (BMP-2) and modified PRP (mPRP) on bone healing was evaluated in vivo. MATERIALS AND METHODS The angiogenic factor-enriched PRP, which included peripheral blood mononuclear cells (mostly lymphocytes and monocytes, excluding… CONTINUE READING

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bined angiogenic and osteogenic factor delivery enhances bone marrow stromal cell - driven bone regeneration

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