Improved biochemical characterization of breast cancer as a guide to hormonal treatment.


Theoretically, all estrogen-receptor positive (ER+) tumors of the breast should respond to hormonal therapy; however, only 50-60% do. Therefore, this study collected information on hormonal variations which affect the cytoplasmic receptor levels and offers other parameters besides estrogenicity for biochemically characterizing breast cancers. One reason ER… (More)