Improved benzodiazepine radioreceptor assay using the MultiScreen Assay System.

  title={Improved benzodiazepine radioreceptor assay using the MultiScreen Assay System.},
  author={Mirjam J Janssen and Kees Ensing and Rokus A de Zeeuw},
  journal={Journal of pharmaceutical and biomedical analysis},
  volume={20 5},
In this article, an improved benzodiazepine radioreceptor assay is described, which allows substantial reduction in assay time. The filtration in this method was performed by using the MultiScreen Assay System. The latter consists of a 96-well plate with glass fibre filters sealed at the bottom, which allows both the incubation and the filtration of the specimen in the same plate. After the filtration, the filters were punched out for quantitation of the bound labeled ligand [3H]flunitrazepam… CONTINUE READING


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