Improved annotation of conjugated bile acid hydrolase superfamily members in Gram-positive bacteria.

@article{Lambert2008ImprovedAO,
  title={Improved annotation of conjugated bile acid hydrolase superfamily members in Gram-positive bacteria.},
  author={Jolanda M Lambert and Roland J. Siezen and Willem M de Vos and Michiel Kleerebezem},
  journal={Microbiology},
  year={2008},
  volume={154 Pt 8},
  pages={2492-500}
}
Most Gram-positive bacteria inhabiting the gastrointestinal tract are capable of hydrolysing bile salts. Bile salt hydrolysis is thought to play an important role in various biological processes in the host. Therefore, correct annotation of bacterial bile salt hydrolases (Bsh) in public databases (EC 3.5.1.24) is of importance, especially for lactobacilli, which are considered to play a major role in bile salt hydrolysis in vivo. In the present study, all enzymes listed in public databases that… CONTINUE READING

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