Improved Method for Tissue Preservation in Murine Atherosclerotic Lesion Tissue

@inproceedings{Bourassa1998ImprovedMF,
  title={Improved Method for Tissue Preservation in Murine Atherosclerotic Lesion Tissue},
  author={Patricia-Ann K. Bourassa and Robert J. Aiello},
  year={1998}
}
AbstractThe ability to evaluate atherosclerotic lesions in animal studies is dependent on the integrity of the tissue of interest. We compared a variety of experimental methods currently in use for preparing and staining atherosclerotic lesions with oil red O in mouse aortic tissue cryosections. We found that perfusion fixation, sucrose infiltration, mounting on Vectabond coated slides, and staining with a propylene glycol based oil red O with Gill I11 hematoxylin as a counterstain enhanced… CONTINUE READING

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