Improved Bioavailability of a Micronized Megestrol Acetate Tablet Formulation in Humans

@article{Farinha2000ImprovedBO,
  title={Improved Bioavailability of a Micronized Megestrol Acetate Tablet Formulation in Humans},
  author={Asçens{\~a}o Farinha and Ant{\'o}nio Bica and Pedro Paulo Lordelo Guimar{\~a}es Tavares},
  journal={Drug Development and Industrial Pharmacy},
  year={2000},
  volume={26},
  pages={567 - 570}
}
Megestrol acetate, a progestogen widely used in the palliative treatment of endometrial carcinoma and breast cancer, is currently administered orally as a solid dosage form. Bioavailability of the drug following oral administration is closely related to the effectiveness and safety profile of the drug in formulation. Improved immediate-release formulations should allow improved drug delivery into the systemic circulation and, at the end, to the site of action. The micronization of drugs is one… 
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