Improved BOLD detection in the medial temporal region using parallel imaging and voxel volume reduction.

@article{Bellgowan2006ImprovedBD,
  title={Improved BOLD detection in the medial temporal region using parallel imaging and voxel volume reduction.},
  author={Patrick S. F. Bellgowan and Peter A. Bandettini and Peter van Gelderen and Alex Martin and Jerzy Bodurka},
  journal={NeuroImage},
  year={2006},
  volume={29 4},
  pages={1244-51}
}
Using gradient-echo EPI, signal dropout due to macroscopic off resonance effects can prevent blood-oxygenation-level-dependent (BOLD) signal change detection. The anterior medial temporal lobe (MTL) is located near these susceptibility gradients and therefore shows considerable signal dropout with GE-EPI. Reducing the volume of the image voxel reduces susceptibility-related signal dropout. However, this is accompanied by a prohibitive reduction in signal-to-noise ratio (SNR). To compensate for… CONTINUE READING