Imprinted Genes, Placental Development and Fetal Growth

@article{Fowden2006ImprintedGP,
  title={Imprinted Genes, Placental Development and Fetal Growth},
  author={A. Fowden and C. Sibley and W. Reik and M. Const{\^a}ncia},
  journal={Hormone Research in Paediatrics},
  year={2006},
  volume={65},
  pages={50 - 58}
}
In mammals, imprinted genes have an important role in feto-placental development. They affect the growth, morphology and nutrient transfer capacity of the placenta and, thereby, control the nutrient supply for fetal growth. In particular, the reciprocally imprinted Igf2–H19 gene complex has a central role in these processes and matches the placental nutrient supply to the fetal nutrient demands for growth. Comparison of Igf2P0 and complete Igf2 null mice has shown that interplay between… Expand
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