Importin 13: a novel mediator of nuclear import and export.

@article{Mingot2001Importin1A,
  title={Importin 13: a novel mediator of nuclear import and export.},
  author={J M Mingot and Susanne Kostka and Regine Kraft and Enno Hartmann and Dirk G{\"o}rlich},
  journal={The EMBO journal},
  year={2001},
  volume={20 14},
  pages={3685-94}
}
Importin beta-related receptors mediate translocation through nuclear pore complexes. Co-operation with the RanGTPase system allows them to bind and subsequently release their substrates on opposite sides of the nuclear envelope, which in turn ensures a directed nucleocytoplasmic transport. Here we identify a novel family member from higher eukaryotes that functions primarily, but not exclusively, in import. It accounts for nuclear accumulation of the SUMO-1/sentrin-conjugating enzyme hUBC9 and… CONTINUE READING
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