Important role of CD18 in TNF-α-induced leukocyte adhesion in muscle and skin venules in vivo

@article{Zhang2000ImportantRO,
  title={Important role of CD18 in TNF-α-induced leukocyte adhesion in muscle and skin venules in vivo},
  author={Xue Wu Zhang and Ren{\'e} Schramm and Qing Liu and H. B. N. Ekberg and Bengt W. Jeppsson and Henrik Thorlacius},
  journal={Inflammation Research},
  year={2000},
  volume={49},
  pages={529-534}
}
Objective: To examine the role of CD18 in tumor necrosis factor-α (TNF-α)-induced leukocyte adhesion and extravasation in vivo.¶Material: Male wild-type (WT) and mutated mice with hypomorphic expression of CD18.¶Methods: Intravital microscopy was used to quantitate leukocyte-endothelium interactions provoked by TNF-α (0.5 μg) in the cremaster muscle and dorsal skin microcirculation. Tissue recruitment of leukocytes was evaluated in whole-mounts of the cremaster muscle and in air pouches in the… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Similar Papers

Loading similar papers…