Importancia de mantener una suficiente concentración sérica de T4 materna en el primer trimestre del embarazo

  • Published 2007


The maternal endocrine system is essential for optimal fetal development, and normal endocrine mechanisms are temporarily supplanted during pregnancy. Transplacental transfer of thyroid hormone plays a crucial role in fetal neurodevelopment throughout ontogeny, especially before mid-gestation when fetal thyroid synthesis becomes significant. Thus, normal… (More)