Importance of the vasoactive intestinal peptide receptor in the stimulation of cyclic adenosine 3',5'-monophosphate in gallbladder epithelial cells of man. Comparison with the guinea pig.

@article{Dupont1981ImportanceOT,
  title={Importance of the vasoactive intestinal peptide receptor in the stimulation of cyclic adenosine 3',5'-monophosphate in gallbladder epithelial cells of man. Comparison with the guinea pig.},
  author={Claire H Dupont and J P Broyart and Y Broer and B Chenut and Marc Laburthe and Gabriel Rosselin},
  journal={The Journal of clinical investigation},
  year={1981},
  volume={67 3},
  pages={742-52}
}
An EDTA procedure was used to prepare isolated epithelial cells of human gallbladder devoid of endogenous vasoactive intestinal peptide (VIP) as measured by radioimmunoassay. Specific binding sites for VIP were characterized in these cells. At 37 degrees C, the binding of (125)I-labeled VIP reached a peak within 20 min and then declined rapidly. At 15 degrees C, binding was stable between 90 and 180 min of incubation. Binding of the labeled peptide was inhibited by concentrations of native VIP… CONTINUE READING

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References

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Showing 1-10 of 21 references

Interac - tion of vasoactive intestinal peptide with isolated epithelial cells from rat . I . Characterization , quantitative aspects , and structural requirements of binding sites

  • B. Amiranoff, C. Dupont, D. Hui Bon Hoa, G. Rosselin
  • Eur . J . Biochem .
  • 1979

Characterization of a vasoactive intestinal peptide sensitive adenylate cyclase in rat intestinal epithelial cell membranes

  • H. G. Friesen
  • Biochim . Biophys . Acta .
  • 1978

The interaction of pancreatic secretagogues with pancreatic plasma membranes

  • P. Fromageot S. Bonfils, G. Rosselin, M. Deschodt-Lanckman, P. Robberecht
  • Hormonal Receptors in Digestive Tract Physiology…
  • 1977

VIP innervation of gallbladder

  • T. N. Keltz, E. Straus, R. S. Yalow
  • Gastroenterology .
  • 1977

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