Importance of the trans-sulfuration pathway in cancer prevention and promotion

@article{Rosado2006ImportanceOT,
  title={Importance of the trans-sulfuration pathway in cancer prevention and promotion},
  author={Joemerson Os{\'o}rio Rosado and Mirian Salvador and Diego Bonatto},
  journal={Molecular and Cellular Biochemistry},
  year={2006},
  volume={301},
  pages={1-12}
}
The trans-sulfuration pathway is a biochemical mechanism that links methionine metabolism to the biosynthesis of cellular redox-controlling molecules, like cysteine, glutathione, and taurine. While there is some knowledge about the metabolic intermediates and enzymes that participate in trans-sulfuration, little is known about the physiological importance of this mechanism. Deficiencies within the trans-sulfuration pathway induces (i) the generation of reactive species of oxygen (ROS) and… CONTINUE READING