Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex.

@article{Wallace2013ImportanceOT,
  title={Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex.},
  author={Tanya L. Wallace and Daniel Bertrand},
  journal={Biochemical pharmacology},
  year={2013},
  volume={85 12},
  pages={1713-20}
}
The prefrontal cortex (PFC) is responsible for integrating cortical and subcortical inputs to execute essential cognitive functions such as attention, working memory planning and decision-making. The importance of this brain region in regulating complex cognitive processes is underscored by a decline in PFC-mediated ability observed in aging and disease. The cholinergic system plays a vital role in cognitive function and treatments (e.g., cholinesterase inhibitors) to improve cholinergic… CONTINUE READING