Importance of surgical margins in conization for cervical intraepithelial neoplasia grade III

Abstract

We conducted a retrospective study on 201 conizations for CIN III done over the last 14 years. Of these, 53 (26.4%) had involvement of the margins, 114 (56.7%) had margins free of neoplasia, and 34 (16.9%) were not evaluated. Of the 53 cases with margin involvement, 28 (52.8%) had complementary surgery and 25 (47.2%) cytological follow-up. Residual CIN was identified in the surgical specimen in 15 cases (53.6%) and microinvasion was present in 2 cases (7.1%). Of the 114 patients with margins free of neoplasia in the cone, 12 had a hysterectomy during follow-up for CIN III diagnosed by cytology and biopsy. Seven of these 12 patients (58.3%) had CIN in the surgical specimen and none had microinvasive cancer.

DOI: 10.1007/s004040050260

2 Figures and Tables

Statistics

0100020002008200920102011201220132014201520162017
Citations per Year

714 Citations

Semantic Scholar estimates that this publication has 714 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Murta1999ImportanceOS, title={Importance of surgical margins in conization for cervical intraepithelial neoplasia grade III}, author={Eddie Fernando Candido Murta and Adara Resende and Maria Helena Souza and Sheila Jorge Adad and Resalla Salum}, journal={Archives of Gynecology and Obstetrics}, year={1999}, volume={263}, pages={42-44} }