Importance of retinoic acid-inducible gene I and of receptor for type I interferon for cellular resistance to infection by Newcastle disease virus.

@article{Fournier2011ImportanceOR,
  title={Importance of retinoic acid-inducible gene I and of receptor for type I interferon for cellular resistance to infection by Newcastle disease virus.},
  author={Philippe Fernandez Fournier and Holger Wilden and Volker Prof Dr Schirrmacher},
  journal={International journal of oncology},
  year={2011},
  volume={40 1},
  pages={
          287-98
        }
}
Newcastle disease virus (NDV) is an avian paramyxovirus with oncolytic properties which shows promising effects in the treatment of cancer. Anti-cancer effects are due to the virus ability: i) to replicate in and kill tumor cells, leading finally to their selective elimination; and ii) to induce the stimulation of antitumor activities in immune cells. NDV does not harm normal cells and has a high safety profile. In this study, we first… CONTINUE READING

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