Importance of nitric oxide in the control of renal hemodynamics.

  title={Importance of nitric oxide in the control of renal hemodynamics.},
  author={Chris Baylis and Changbin Qiu},
  journal={Kidney international},
  volume={49 6},
The kidney vasculature is under tonic control by nitric oxide (NO) and in cortex, NO controls RA and Kf. Systemic NO inhibition leads to systemic hypertension, increases in RE, mediated by Ang II and ET, and direct effects on RA and Kf. The relationship between NO and other vasoconstrictor systems is variable. In the conscious relaxed animal, vasoconstrictor activity is low, yet acute NO inhibition leads to pressor and renal vasoconstrictor responses. At physiologic levels, ET unexpectedly is a… CONTINUE READING


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