Importance of macrophage cholesterol content on the flux of cholesterol mass.

@article{Sankaranarayanan2010ImportanceOM,
  title={Importance of macrophage cholesterol content on the flux of cholesterol mass.},
  author={Sandhya Sankaranarayanan and Margarita de la Llera-Moya and Denise Drazul-Schrader and Bela F. Asztalos and Ginny L Weibel and George H. Rothblat},
  journal={Journal of lipid research},
  year={2010},
  volume={51 11},
  pages={3243-9}
}
Net flux of cholesterol represents the difference between efflux and influx and can result in net cell-cholesterol accumulation, net cell-cholesterol depletion, or no change in cellular cholesterol content. We measured radiolabeled cell-cholesterol efflux and cell-cholesterol mass using cholesterol-normal and -enriched J774 and elicited mouse peritoneal macrophage cells. Net cell-cholesterol effluxes were observed when cholesterol-enriched J774 cells were incubated with 3.5% apolipoprotein (apo… CONTINUE READING

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