Importance of juvenile hormone signaling arises with competence of insect larvae to metamorphose.

@article{Smkal2014ImportanceOJ,
  title={Importance of juvenile hormone signaling arises with competence of insect larvae to metamorphose.},
  author={Vlastimil Sm{\'y}kal and Takaaki Daimon and Takumi Kayukawa and Keiko Takaki and Tetsuro Shinoda and Marek Jindra},
  journal={Developmental biology},
  year={2014},
  volume={390 2},
  pages={221-30}
}
Juvenile hormone (JH) postpones metamorphosis of insect larvae until they have attained an appropriate stage and size. Then, during the final larval instar, a drop in JH secretion permits a metamorphic molt that transforms larvae to adults either directly (hemimetaboly) or via a pupal stage (holometaboly). In both scenarios, JH precludes metamorphosis by activating the Kr-h1 gene through a JH receptor, Methoprene-tolerant (Met). Removal of Met, Kr-h1, or JH itself triggers deleterious… CONTINUE READING

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