Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice.

Abstract

OBJECTIVE Although junctional adhesion molecule-A (JAM-A) has recently been implicated in leukocyte recruitment on early atherosclerotic endothelium and after reperfusion injury, its role in neointima formation after arterial injury remains to be elucidated. METHODS AND RESULTS Here we show that the genetic deletion of JAM-A in apolipoprotein E-deficient… (More)

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