Importance of gastrin in the pathogenesis and treatment of gastric tumors.

@article{Burkitt2009ImportanceOG,
  title={Importance of gastrin in the pathogenesis and treatment of gastric tumors.},
  author={Michael D Burkitt and Andrea Varr{\'o} and D Mark Pritchard},
  journal={World journal of gastroenterology},
  year={2009},
  volume={15 1},
  pages={1-16}
}
In addition to regulating acid secretion, the gastric antral hormone gastrin regulates several important cellular processes in the gastric epithelium including proliferation, apoptosis, migration, invasion, tissue remodelling and angiogenesis. Elevated serum concentrations of this hormone are caused by many conditions, particularly hypochlorhydria (as a result of autoimmune or Helicobacter pylori (H pylori)-induced chronic atrophic gastritis or acid suppressing drugs) and gastrin producing… CONTINUE READING

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