Importance of collection in gene set enrichment analysis of drug response in cancer cell lines


Gene set enrichment analysis (GSEA) associates gene sets and phenotypes, its use is predicated on the choice of a pre-defined collection of sets. The defacto standard implementation of GSEA provides seven collections yet there are no guidelines for the choice of collections and the impact of such choice, if any, is unknown. Here we compare each of the… (More)
DOI: 10.1038/srep04092


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