Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease.

@article{Chao1991ImportanceOB,
  title={Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease.},
  author={Nelson J Chao and Auayporn P. Nademanee and Gwynn D. Long and Gerhard M. Schmidt and Timothy A. Donlon and Pablo Parker and Marilyn L. Slovak and L S Nagasawa and Karl G. Blume and Stephen J. Forman},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1991},
  volume={9 9},
  pages={1575-9}
}
Alkylating agents used either with or without radiation therapy have been associated with the development of myelodysplastic syndrome (MDS) and acute nonlymphoblastic leukemia (ANLL) after treatment of both malignant and nonmalignant disorders. This report describes seven patients with recurrent Hodgkin's disease (HD) evaluated for bone marrow transplantation (BMT) who developed chromosomal abnormalities, and emphasizes the importance of bone marrow cytogenetic studies before bone marrow… CONTINUE READING

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