Importance of a Myosin II-Containing Progenitor for Actomyosin Ring Assembly in Fission Yeast

  title={Importance of a Myosin II-Containing Progenitor for Actomyosin Ring Assembly in Fission Yeast},
  author={Kelvin C.Y. Wong and Ventris M. D'souza and Naweed I Naqvi and Fumio Motegi and Issei Mabuchi and Mohan K Balasubramanian},
  journal={Current Biology},
An actomyosin-based contractile ring provides the forces necessary for cell cleavage in several organisms [1-3]. Myosin II is an essential component of the actomyosin ring and has also been detected as a "spot" in interphase Schizosaccharomyces pombe cells [4-5]. It is currently unknown if this myosin II-containing spot is important for cytokinesis. In this study, we characterize this myosin II-containing spot using a combination of genetic and cell biological analyses. Whereas myosin II at the… CONTINUE READING


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