Importance of NOD2/CARD15 gene variants for susceptibility to and outcome of sepsis in Turkish children.

Abstract

OBJECTIVE Severe sepsis remains a leading cause of morbidity and mortality in children. Given the link to pathogenesis, polymorphisms in genes involved in infection and inflammation may influence the outcomes in patients with sepsis and septic shock. The role of mutations within the innate immunity receptor NOD2/CARD15 has recently been demonstrated as a… (More)
DOI: 10.1097/PCC.0b013e3182191c2e

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