Importance of Both Innate Immunity and Acquired Immunity for Rapid Expulsion of S. venezuelensis

@inproceedings{Yasuda2014ImportanceOB,
  title={Importance of Both Innate Immunity and Acquired Immunity for Rapid Expulsion of S. venezuelensis},
  author={Koubun Yasuda and Makoto Matsumoto and Kenji Nakanishi},
  booktitle={Front. Immunol.},
  year={2014}
}
In the first part of this review, we described the relevant roles of endogenous IL-33 for accumulation of ILC2 and eosinophils even in the lungs of Rag2(-/-) mice. Type II alveolar epithelial (ATII) cells express IL-33 in their nucleus and infection with Strongyloides venezuelensis induces IL-33 production by increasing the number of ATII cells possibly by the action of chitin. IL-33 from ATII cells induces ILC2 proliferation and at the same time activates them to produce IL-5 and IL-13, which… CONTINUE READING
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