Importance, localization and functional properties of the cell-associated form of plasminogen activator in mouse peritoneal macrophages.

@article{Lemaire1983ImportanceLA,
  title={Importance, localization and functional properties of the cell-associated form of plasminogen activator in mouse peritoneal macrophages.},
  author={Genevi{\`e}ve Lemaire and Jean Claude Drapier and J F Petit},
  journal={Biochimica et biophysica acta},
  year={1983},
  volume={755 3},
  pages={332-43}
}
In inflammatory macrophages, plasminogen activator exists in two active forms, a soluble form released into the extracellular medium and a cell-associated form. This communication describes some properties of the cellular form of plasminogen activator, in intact macrophages and in cell lysates. Cellular plasminogen activator is a membrane protein, associated with the outer face of the plasma membrane; in intact macrophages, it participates in the activation of exogenous plasminogen and, thus… CONTINUE READING