Implications of the impact of prevalence on test thresholds and outcomes: lessons from tuberculosis

@inproceedings{Bentley2012ImplicationsOT,
  title={Implications of the impact of prevalence on test thresholds and outcomes: lessons from tuberculosis},
  author={Tanya G. K. Bentley and Antonino Catanzaro and Theodore G Ganiats},
  booktitle={BMC Research Notes},
  year={2012}
}
With today’s rapid advances in technology and understanding of disease, more screening and diagnostic tests have become available in a variety of sociodemographic and clinical settings. This analysis quantifies the impact of varying prevalence rates on test performance for given sensitivity and specificity values. Using a worked example of latent tuberculosis infection, we compared true-positive (TP) and false-positive (FP) results when varying prevalence and test sensitivity and specificity… CONTINUE READING