Implications of the gut microbiota in vulnerability to the social avoidance effects of chronic social defeat in male mice

@article{Szyszkowicz2017ImplicationsOT,
  title={Implications of the gut microbiota in vulnerability to the social avoidance effects of chronic social defeat in male mice},
  author={Joanna Kasia Szyszkowicz and Alex Wong and Hymie Anisman and Zul Merali and M Audet},
  journal={Brain, Behavior, and Immunity},
  year={2017},
  volume={66},
  pages={45-55}
}
Appreciable evidence suggests that perturbations within the gut microbiome and the immune system may play a key role in the pathogenesis of depression stemming from earlier stressful experiences. In the present investigation we examined whether microbial changes in cecum contents were associated with social avoidance behaviors, a feature of depression, and pro-inflammatory variations among socially stressed mice. Male C57BL/6 mice experienced social defeat or a control condition once a day for… CONTINUE READING
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Implications of the gut microbiota in vulnerability to the social avoidance effects of chronic social defeat in male mice, Brain, Behavior, and Immunity

J. K. Szyszkowicz, A. Wong, +3 authors M-C
  • 2017