Implications of the dependence of the elastic properties of DNA on nucleotide sequence.

@article{Olson2004ImplicationsOT,
  title={Implications of the dependence of the elastic properties of DNA on nucleotide sequence.},
  author={Wilma K. Olson and David Swigon and Bernard D. Coleman},
  journal={Philosophical transactions. Series A, Mathematical, physical, and engineering sciences},
  year={2004},
  volume={362 1820},
  pages={1403-22}
}
Recent advances in structural biochemistry have provided evidence that not only the geometric properties but also the elastic moduli of duplex DNA are strongly dependent on nucleotide sequence in a way that is not accounted for by classical rod models of the Kirchhoff type. A theory of sequence-dependent DNA elasticity is employed here to calculate the… CONTINUE READING