Implications of tachykinins and calcitonin gene-related peptide in inflammatory bowel disease.

@article{Holzer1998ImplicationsOT,
  title={Implications of tachykinins and calcitonin gene-related peptide in inflammatory bowel disease.},
  author={Peter Holzer},
  journal={Digestion},
  year={1998},
  volume={59 4},
  pages={269-83}
}
Calcitonin gene-related peptide (CGRP) and the preprotachykinin A gene-derived peptides substance P (SP) and neurokinin A (NKA) are expressed in extrinsic primary afferent nerve fibres and intrinsic enteric neurons of the gut. The actions of tachykinins on the digestive effector systems are mediated by three different types of tachykinin receptor, termed NK1, NK2 and NK3 receptors, while the gastro-intestinal actions of CGRP are brought about by CGRP1 and possibly other CGRP receptors. These… CONTINUE READING
38 Citations
143 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 143 references

Similar Papers

Loading similar papers…