Implications of sleep disturbance and inflammation for Alzheimer's disease dementia

@article{Irwin2019ImplicationsOS,
  title={Implications of sleep disturbance and inflammation for Alzheimer's disease dementia},
  author={M. Irwin and M. Vitiello},
  journal={The Lancet Neurology},
  year={2019},
  volume={18},
  pages={296-306}
}
Nearly half of all adults older than 60 years of age report sleep disturbance, as characterised either by reports of insomnia complaints with daytime consequences, dissatisfaction with sleep quality or quantity, or the diagnosis of insomnia disorder. Accumulating evidence shows that sleep disturbance contributes to cognitive decline and might also increase the risk of Alzheimer's disease dementia by increasing β-amyloid burden. That sleep disturbance would be a candidate risk factor for… Expand
Local Sleep and Alzheimer’s Disease Pathophysiology
  • B. Mander
  • Medicine
  • Frontiers in Neuroscience
  • 2020
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