Implications of pharmacogenomics for drug development and clinical practice.

  title={Implications of pharmacogenomics for drug development and clinical practice.},
  author={Geoffrey S. Ginsburg and Richard P. Konstance and Jennifer S Allsbrook and Kevin A. Schulman},
  journal={Archives of internal medicine},
  volume={165 20},
Pharmacogenomics is likely to be among the first clinical applications of the Human Genome Project and is certain to have an enormous impact on the clinical practice of medicine. Herein, we discuss the potential implications of pharmacogenomics on the drug development process, including drug safety, productivity, market segmentation, market expansion, differentiation, and personalized health care. We also review 3 challenges facing the translation of pharmacogenomics into clinical practice… CONTINUE READING

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