Implications of laboratory diagnosis on brucellosis therapy

  title={Implications of laboratory diagnosis on brucellosis therapy},
  author={Sascha Al Dahouk and Karsten Nöckler},
  journal={Expert Review of Anti-infective Therapy},
  pages={833 - 845}
Brucellosis is a worldwide zoonosis with a huge economic impact on animal husbandry and public health. The diagnosis of human brucellosis can be protracted because the disease primarily presents as fever of unknown origin with unspecific clinical signs and symptoms. The isolation rate of the fastidious etiologic agent from blood cultures is low, and therefore laboratory diagnosis is mainly based on serologic and molecular testing. However, seronegative brucellosis patients have been described… 
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