Implications of chronic methamphetamine use: a literature review.

@article{Meredith2005ImplicationsOC,
  title={Implications of chronic methamphetamine use: a literature review.},
  author={Charles W. Meredith and Craig Jaffe and Kathleen Ang-Lee and Andrew J. Saxon},
  journal={Harvard review of psychiatry},
  year={2005},
  volume={13 3},
  pages={
          141-54
        }
}
Methamphetamine (MA) abuse is increasing to epidemic proportions, both nationally and globally. Chronic MA use has been linked to significant impairments in different arenas of neuropsychological function. To better understand this issue, a computerized literature search (PubMed, 1964-2004) was used to collect research studies examining the neurobiological and neuropsychiatric consequences of chronic MA use. Availability of MA has markedly increased in the United States due to recent… 
Does Chronic Methamphetamine Use Result in a Consistent Profile of Cognitive Deficits
Methamphetamine (MA) use in the United States is a significant problem that spans across the nation. While research has focused on specific domains affected by MA use there is limited research in
Neurocognitive Effects of Methamphetamine: A Critical Review and Meta-analysis
TLDR
A meta-analysis of the neuropsychological effects of MA abuse/dependence revealed broadly medium effect sizes, showing deficits in episodic memory, executive functions, information processing speed, motor skills, language, and visuoconstructional abilities.
Psychosocial Correlates of Methamphetamine Use
Methamphetamine (MA) abuse is a devastating problem that has been sweeping the United States from west to east and has reached epidemic proportion in many areas. Literature on the drug itself, its
Clinical Aspects of Methamphetamine
TLDR
The historical underpinnings of the methamphetamine problem are introduced, the neurobiological impact of methamphetamine is described, and the health and social factors associated with methamphetamine use are reviewed, to highlight the key subgroups at risk for methamphetamine problems.
A review of the clinical pharmacology of methamphetamine.
TLDR
Repeated use of methamphetamine may induce neurotoxicity, associated with prolonged psychiatric symptoms, cognitive impairment and an increased risk of developing Parkinson's disease.
Methamphetamine abuse and impairment of social functioning: a review of the underlying neurophysiological causes and behavioral implications.
TLDR
The reviewed literature provides strong circumstantial evidence that social-cognitive functioning is significantly impacted by methamphetamine use and that the social isolation, depression, and aggressiveness associated with chronic use is due to more than just the social withdrawal associated with addiction.
Methamphetamine Dependence : A Double-blind Controlled , Crossover Study
TLDR
Current standard treatment of METH dependence is the Matrix Model, which combines cognitive, behavioral, and psychological approaches of Meth dependency, which may improves compliance and reduces the relapse.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 225 REFERENCES
Treatment of methamphetamine use disorders: an update.
History of the Methamphetamine Problem
TLDR
The burgeoning problems of increased MA use must be addressed by adequate treatment programs suitable for a variety of user types, and optimum treatment for MA abusers relies on an intensive outpatient setting with three to five visits per week of comprehensive counseling.
Integrating treatments for methamphetamine abuse: a psychosocial perspective.
TLDR
It is suggested that while there are important differences in group characteristics and drug effects, the total response to treatment was quite comparable, and the next few years will likely witness a substantial increase in treatment research on methamphetamine abuse/dependence.
Patterns of Methamphetamine Abuse and Their Consequences
TLDR
The intensity of METH actions in the central and peripheral nervous system shows tolerance after chronic administration, indicating that neuro-adaptations have occurred and contribute to the craving and dependence associated with METH abuse and the withdrawal syndrome upon abstinence.
Neuropsychological effects of chronic methamphetamine use on neurotransmitters and cognition: a review.
TLDR
A selective review provides an outline and synthesis of studies that assess the neurotoxic mechanisms of methamphetamine, as well as those that evaluate the cognitive sequelae of methamphetamine abuse.
Cognitive Deficits Among Methamphetamine Users with Attention Deficit Hyperactivity Disorder Symptomatology
TLDR
The preliminary data suggests that executive function deficits and some of the symptoms associated with long-term MA use may be due to the fact that a large proportion of MA addicts had ADHD symptomatology as children.
Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers.
TLDR
Evidence is provided that methamphetamine at dose levels taken by human abusers of the drug leads to dopamine transporter reduction that is associated with motor and cognitive impairment and the urgency of alerting clinicians and the public of the long-term changes that methamphetamine can induce in the human brain.
Evidence for long-term neurotoxicity associated with methamphetamine abuse
TLDR
Evidence for long-term neuronal damage in abstinent methamphetamine users is provided by the reduced N-acetylaspartate on 1H MRS, which was reduced significantly in the basal ganglia and frontal white matter of methamphetamine users compared with control subjects.
...
1
2
3
4
5
...