Implications of Plasma Renin Activity and Plasma Aldosterone Concentration in Critically Ill Patients with Septic Shock

@inproceedings{Chung2017ImplicationsOP,
  title={Implications of Plasma Renin Activity and Plasma Aldosterone Concentration in Critically Ill Patients with Septic Shock},
  author={Kyung Soo Chung and Joo Han Song and Won Jai Jung and Young Sam Kim and Se Kyu Kim and Joon Chang and Moo Suk Park},
  year={2017}
}
High morbidity and mortality from severe sepsis and septic shock is still an unresolved challenging [1,2]. Sepsisinduced tissue hypoperfusion and organ dysfunction result from vasodilation, decreased systemic vascular resistance, and increased microvascular leakage [3]. Hypotension triggers a complex neurohumoral response during severe sepsis to maintain blood pressure homeostasis, resulting in increased sympathetic responses and hypothalamic–pituitary–adreKorean J Crit Care Med 2017 May 32(2… CONTINUE READING

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