Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis

@article{Wang1994ImplicationsFB,
  title={Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis},
  author={Shengxian Wang and Tulle Hazelrigg},
  journal={Nature},
  year={1994},
  volume={369},
  pages={400-403}
}
SUBCELLULAR RNA localization in different cell types leads to asymmetric distribution of proteins in these cells1,2. The localization of bicoid (bcd) messenger RNA to the anterior pole of the developing Drosophila oocyte gives rise in embryogenesis to a steep concentration gradient of the bcd protein3–6, a transcription factor that activates expression of zygotic genes needed for anterior development7–9. The exuperantia (exu) gene is necessary for this localization of bcd mRNA3,4. Here we… CONTINUE READING

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