Implication of toll-like receptor and tumor necrosis factor α signaling in septic shock

@inproceedings{Lin2005ImplicationOT,
  title={Implication of toll-like receptor and tumor necrosis factor α signaling in septic shock},
  author={Wen-Jye Lin and Wen-chen Yeh},
  year={2005}
}
Septic shock is initiated by a systemic inflammatory response to microbial infection that frequently leads to impaired perfusion and multiple organ failure. Because of its high risk of death, septic shock is a major problem particularly for patients in the intensive care unit. In general, bacterial lipopolysaccharide (LPS) is a strong activator of various immune responses and stimulates monocytes/macrophages to release a variety of inflammatory cytokines. However, over- production of… CONTINUE READING

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