Implication of brain-derived neurotrophic factor in the release of dopamine and dopamine-related behaviors induced by methamphetamine

@article{Narita2003ImplicationOB,
  title={Implication of brain-derived neurotrophic factor in the release of dopamine and dopamine-related behaviors induced by methamphetamine},
  author={Minoru Narita and Kazuhiro Aoki and Masatoshi Takagi and Yoshinori Yajima and Tsutomu Suzuki},
  journal={Neuroscience},
  year={2003},
  volume={119},
  pages={767-775}
}
It is widely recognized that methamphetamine enhances the release of dopamine at dopaminergic neuron terminals of the mesolimbic system, which induces dopamine-related behaviors. Brain-derived neurotrophic factor (BDNF), a neurotrophin, binds to and activates its specific receptor tyrosine kinase, TrkB. BDNF has been shown to influence the release of dopamine in the mesolimbic dopamine system. The present study was designed to investigate roles of BDNF and TrkB in the expression of… CONTINUE READING

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