Implication of MYH in colorectal polyposis.

  title={Implication of MYH in colorectal polyposis.},
  author={J{\'e}r{\'e}mie H Lefevre and Christelle M Rodrigue and Najat Mourra and Malika Bennis and Jean-François Fl{\'e}jou and Rolland Parc and Emmanuel Tiret and Christian P Gespach and Yann R Parc},
  journal={Annals of surgery},
  volume={244 6},
  pages={874-9; discussion 879-80}
OBJECTIVE The aim of this study was to determine the frequency of MYH mutations in one large population of polyposis patients without APC mutation identified. SUMMARY BACKGROUND DATA Familial adenomatous polyposis (FAP) is the most known inherited colorectal cancer syndrome. In 70% to 80% of polyposis patients, an APC mutation is found. Patients with polyposis but no APC mutation are considered as APC-muted patients and followed as their relatives accordingly. Biallelic mutation of MYH has… CONTINUE READING

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